A Longitudinal View at the Adoption of Multipath TCP

Multipath TCP (MPTCP) extends traditional TCP to enable simultaneous use ofmultiple connection endpoints at the source and destination. MPTCP has beenunder active development since its standardization in 2013, and more recentlyin February 2020, MPTCP was upstreamed to the Linux kernel. In this paper, weprovide an in-depth analysis of MPTCPv0 in the Internet and the first analysisof MPTCPv1 to date. We probe the entire IPv4 address space and an IPv6 hitlistto detect MPTCP-enabled systems operational on port 80 and 443. Our scansreveal a steady increase in MPTCPv0-capable IPs, reaching 13k+ on IPv4(2$\times$ increase in one year) and 1k on IPv6 (40$\times$ increase). MPTCPv1deployment is comparatively low with $\approx$100 supporting hosts in IPv4 andIPv6, most of which belong to Apple. We also discover a substantial share ofseemingly MPTCP-capable hosts, an artifact of middleboxes mirroring TCPoptions. We conduct targeted HTTP(S) measurements towards select hosts and findthat middleboxes can aggressively impact the perceived quality of applicationsutilizing MPTCP. Finally, we analyze two complementary traffic traces fromCAIDA and MAWI to shed light on the real-world usage of MPTCP. We find thatwhile MPTCP usage has increased by a factor of 20 over the past few years, itstraffic share is still quite low.<br

Derivative UV/Vis spectroelectrochemistry in a thin-layer regime: deconvolution and simultaneous quantification of ascorbic acid, dopamine and uric acid

In this work, UV/Vis spectroelectrochemistry (SEC), in a thin-layer regime and parallel configuration, is selected to solve a complex mixture that contains dopamine (DA), ascorbic acid (AA) and uric acid (UA). These molecules, like many other biological compounds, are assuming a highly important place in analytical and biomedical fields due to the fundamental role that they play in human metabolism. In addition, low or high levels of these compounds are associated with diseases such as Parkinson’s disease. For this reason, the quantification of these biomolecules is becoming increasingly critical. However, some drawbacks must be overcome, because the three molecules coexist in the human body, and the species are subject to mutual interference. In fact, they are all oxidized at similar potentials, and their UV/Vis absorption bands overlap, greatly complicating their quantification. For this reason, derivative SEC together with suitable chemometric tools such as PARAFAC are proposed to solve this complex matrix. This technique allows us to separate the contribution of each of these molecules present in a sample and to quantify all of them, achieving high resolution and reproducibility. Besides, detection limits at the micromolar level are achieved for DA, AA and UA in mixture solutions. This work thus demonstrates the great potential for derivative potentiodynamic SEC combined with the appropriate chemometric tools in solving complex mixtures, a field where SEC is still taking the first steps.Ministerio de Economía y Competitividad (Grants CTQ2017-83935-RAEI/ FEDER, UE), Junta de Castilla y León (Grant BU297P18) and Ministerio de Ciencia, Innovación y Universidades (RED2018-102412- T). F.O. is grateful for the contract funded by Junta de Castilla y León, the European Social Fund and the Youth Employment Initiative. J.G.R. thanks theMinisterio de Economía y Competitividad for his postdoctoral contract (CTQ2017-83935-R AEI/FEDER, UE)

Quality of Financial Reporting, Investment and Quality of Disclosure: With Stressing on Type of FinancingQuality of Financial Reporting, Investment and Quality of Disclosure: With Stressing on Type of Financing

Abstract: I

SemEval-2022 Task 8: multilingual news article similarity

Thousands of new news articles appear daily in outlets in different languages. Understanding which articles refer to the same story can not only improve applications like news aggregation but enable cross-linguistic analysis of media consumption and attention. However, assessing the similarity of stories in news articles is challenging due to the different dimensions in which a story might vary, e.g., two articles may have substantial textual overlap but describe similar events that happened years apart. To address this challenge, we introduce a new dataset of nearly 10,000 news article pairs spanning 18 language combinations annotated for seven dimensions of similarity as SemEval 2022 Task 8. Here, we present an overview of the task, the best performing submissions, and the frontiers and challenges for measuring multilingual news article similarity. While the participants of this SemEval task contributed very strong models, achieving up to 0.818 correlation with gold standard labels across languages, human annotators are capable of reaching higher correlations, suggesting space for further progress

Multiphoton Fabrication of Proteinaceous Nanocomposite Microstructures with Photothermal Activity in the Infrared

Two-photon laser writing is used here to fabricate 3D proteinaceous microstructures with photothermal functionality in the near-infrared spectral region and tunable elasticity. The photo-cross-linking is initiated in bovine serum albumin (BSA) by rose bengal or methylene blue and the photo-thermal effect arises from gold non-spherically symmetric nanoparticles dispersed in the ink. Massive energy transfer of the plasmonic resonances of the gold nanoparticles to methylene blue prevents effective photo-crosslinking of BSA. However, stable microstructures with photo-thermal functionality can be fabricated in the rose bengal proteinaceous inks. On these microstructures, with a gold atom concentration as low as 1% w/w, a highly localized temperature increase can be quickly (≅1 s) reached and maintained under continuous wave laser irradiation at 800 nm. The photothermal efficiency under continuous wave laser irradiation depends on the thickness of the microstructure and can reach 12.2 ± 0.4 °C W−1 These proteinaceous microstructures represent therefore a promising platform for future applications in the fields like physical stimulation of cells for regenerative nanomedicine